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Gemmill, Robert
One or more keywords matched the following properties of Gemmill, Robert
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keywords Lung cancer
overview Dr. Gemmill studies cancer-linked chromosome aberrations and genetic alterations in both lung cancers and kidney cancers. Specifically he investigates the role of the epithelial-mesenchymal transition (EMT) in disease progression and drug resistance. His laboratory has studied multiple target genes, including SEMA3F, several EMT transcriptional repressors (ZEB1, ZEB2, SNAIL, SLUG) and is testing some as biomarkers using a novel Photonic Crystal detection platform.
One or more keywords matched the following items that are connected to Gemmill, Robert
Item TypeName
Academic Article Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention.
Academic Article PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers.
Academic Article Chromosomal duplication accompanies allelic loss in non-small cell lung carcinoma.
Academic Article DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC.
Academic Article Molecular definition of a small amplification domain within 3q26 in tumors of cervix, ovary, and lung.
Academic Article Angiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancer.
Academic Article WNT7a induces E-cadherin in lung cancer cells.
Academic Article Selective suppression of in vivo tumorigenicity by semaphorin SEMA3F in lung cancer cells.
Academic Article Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.
Academic Article Altered HOX and WNT7A expression in human lung cancer.
Academic Article Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells.
Academic Article ZEB-1, a repressor of the semaphorin 3F tumor suppressor gene in lung cancer cells.
Academic Article Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas.
Academic Article Induction of E-cadherin in lung cancer and interaction with growth suppression by histone deacetylase inhibition.
Academic Article High-throughput tissue microarray analysis used to evaluate biology and prognostic significance of the E-cadherin pathway in non-small-cell lung cancer.
Academic Article Multiplexed specific label-free detection of NCI-H358 lung cancer cell line lysates with silicon based photonic crystal microcavity biosensors.
Academic Article YAC contigs covering an 8-megabase region of 3p deleted in the small-cell lung cancer cell line U2020.
Academic Article Characterization of the submicroscopic deletion in the small-cell lung carcinoma (SCLC) cell line U2020.
Academic Article Distinct 3p21.3 deletions in lung cancer and identification of a new human semaphorin.
Academic Article Homozygous deletions of human chromosome 3p in lung tumors.
Academic Article Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.
Academic Article MYC and EIF3H Coamplification significantly improve response and survival of non-small cell lung cancer patients (NSCLC) treated with gefitinib.
Academic Article ZEB1-responsive genes in non-small cell lung cancer.
Academic Article Phase 1 clinical trial of the novel proteasome inhibitor marizomib with the histone deacetylase inhibitor vorinostat in patients with melanoma, pancreatic and lung cancer based on in vitro assessments of the combination.
Academic Article Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene.
Concept Lung Neoplasms
Academic Article Neuropilin-2 Is upregulated in lung cancer cells during TGF-?1-induced epithelial-mesenchymal transition.
Academic Article Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells.
Academic Article ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.
Academic Article Erratum: Roche, J. et al. Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells. Cancers, 2013, 5, 334-356.
Academic Article The neuropilin 2 isoform NRP2b uniquely supports TGF?-mediated progression in lung cancer.
Academic Article Epigenetic Regulation of the Epithelial to Mesenchymal Transition in Lung Cancer.
Academic Article A triad of NRP2, DLX and p53 proteins in lung cancer metastasis.
Academic Article Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non-small cell lung cancer.
Search Criteria
  • Lung Neoplasms